Back in the olden days (the '80's), when Metallic Handgun Silhouette Shooting was becoming popular, lots of folks were using Model 29s for competition. Many of these shooters were handloading to very high pressures and putting lots of lead downrange. This caused excessive wear on the Model 29 and there were more than a few that experienced cylinder unlocking, rotation, and timing issues. Shooters were taking their guns in to have modifications done, including installation of a ball detent in the frame in the front of the cylinder crane to act as an additional locking lug. In response S&W came out with their endurance package. This is a long winded way of saying that, unless you will be hot loading and shooting TONS of ammunition, I don't think you're going to have an issue.