Difficult to determine from the photo but my vote is a type of prickly lettuce and yes prickly lettuce is a close relative of commercially grown lettuce. And it is edible but you want it considerably younger, and smaller, than this specimen.
Don't mean to be a butt-head but I actually have an earned PhD in weed science (NCSU 1986). You can get a PhD in just about anything! But in all candor, taxonomy through photos has never been a particular strength of mine. I am in error about things several times a day.
I have a bunch growing around here. I thought they were from seeds mistakenly thrown by my fence by, uh, the neighbor kids, yeah, but they’re just useless weeds. I mean useless, I heard.
Here's a pic of hemp in a Texas AgriLife (extension service) variety trial from last summer. We're trying to find a variety adapted to Texas conditions that yields decent fiber. It turns out it's a bit of a task. And no; I'm not that kind of weed scientist.
Several posts referred to "useless" plants and that is pretty close to the actual, working, definition of what constitutes a weed. It's all based on anthropomorphism (people-orientation).
A weed is a plant for which an economic use has yet to be identified, or a plant growing "out-of-place." Hence prickly lettuce is a non-economically important plant and therefore a weed. And so is a corn plant growing in a field planted to soybeans.