The pin, or at least the way they used to be fitted, allow a rather startling amount of rotation before they interfere.
And yes, torque reaction of the barrel to rotating the bullet will tend to tighten a S&W barrel (and the Colt left hand twist to loosen), but it does require a barrel that didn't have proper torque in installation.
There have been a couple of threads on here, and some old gunsmithing books, that suggest slightly peening the shoulder of the barrel (out of the gun) or putting prick punch marks on the frame shoulder (guess you could do that to the barrel shoulder) to provide a smidgen of extra metal to try to get correct torque. Either method depends upon exactly how much metal needs to be added to the barrel shoulder. My semi-educated guess (been too long since I was doing barrels) is that it's more than you're likely to get through either method.
I'd be reluctant to use thread lockers. You might try checking with S&W to see if they can/will help you out. Setting the barrel back would really be the right way to do it, but can be costly depending. Don't know any 'smiths in Florida.