I have Crimson Trace LG-305 lasergrips on three j-frames, a pair of 642-2 and a 649-5. I use the 642s as pocket holster-carried backup to my IWB-carried auto. I have never found that the LG-305s interfere with drawing smoothly or quickly from my pockets. I like the grip angle that the 305 gives my j-frames; it seems similar to my Glock autos. I find that the long covered-backstrap 305 helps tame recoil with +P loads, compared to the OEM boot grips. YMMV.
Have never tried any of the other j-frame lasergrips so I can't make a comparison.
Here are my general thoughts on laser sights on handguns. IMO lasergrips are most useful under moderate to low light conditions, and are worthless in bright sunshine.
They are more useful, relatively speaking, on a gun with lousy hard-to-see can't-be-adjusted sights (like a j-frame) than on a gun with nice big square easy-to-see iron, white dot, or tritium sights.
I find that lasers are slower to pick up visually than a good set of white dot or tritium iron sights, assuming there is enough light to actually see the iron sights.
Lasers also can help folks who have presbyopia or other vision issues that make it difficult to focus on the front sight.
Adding a laser to a gun actually offers an additional training challenge compared to iron sights. They can make the gun easier and faster to shoot under certain conditions, but only if the user does the extra training to learn how to use them effectively, and to understand their capabilities and limitations.