Vail's probably right on that about the hollowpoints. I don't recall that I've ever seen a hollowpoint come out of a human looking like those that show up in magazine ads. "Moderate deformation" is the descriptor that I see a lot in OMI reports. I'm sure you get some good ones from time to time (Mas has some cases, I believe), but certainly one shouldn't get too wrapped up in hollowpoint performance.
I don't believe that expansion is any sort of important in handgun effectiveness on people, though (I like hollowpoints mainly for their tendency not to overpenetrate). And I have worked on two cases in which pathologists could not tell the wound tracks left by fat bullets from those left by middling bullets.
RE: the 10s and .41s. I really like those. But I can tell you that I can't shoot them fast if they're the heavy and moderately fast ones. And I don't really know anyone who can or does. Plus, the overpenetration worries are a concern.
The Feebies have pretty good science on this, and, based on that, they backed away from the full-power 10s to what became the Short & Weak. I loaded up a whole mess of .41s just yesterday: a bunch of hot 215-grainers over a max charge of Lil' Gun for hiking up Bear Canyon, and a whole bunch of the same LSWCs over a moderate charge of SR 7625 to get me just over 1k fps from my 4" 57. Those are what I'd carry: I can shoot them rapidly and accurately, and I can practice with them until the cows come home. Plus, I don't think they'd be so likely to come blasting through an ED and continue on through the school bus, the nursing home, the grocery store, etc.