I've been bitten a couple of times by spiders, according to my doc even a large "wolf spider" or "housespider" can cause a reaction in some people. I had my leg swell up once, got real red and angry looking, we cooked up a poltice and it got well in a couple days. Another time I had grabbed a jacket off the wall it had been hanging on for a couple months and pulled it on without even thinking to shake it out, I worked out in the shop for hours and went in late for dinner. My wrist had an itchy spot, like a skeeter had bit me. In the morning I noticed the wrist was slightly swollen and angry red, felt hot to the touch. I got through that day and knew I would be back in town the next so I let it go. When I got up Monday I had what felt like water under my skin way past half-way up my arm, I drove down to the local doc in a box...Doc said "That would have cost you your arm not too many years ago." He said spiders cause more injury through infection than anything else, I had cellulitis or infection under my skin, a shot of penicillin and I was good to go. A buddy of mine ened up with a hole in his leg that started out as a red bump, progressed to a red bump with a purple ring, then the whole thing turned purple, then black, then started sinking...he went to the doc. They ended up having to give him skin grafts, that skin rotted right down to his major leg bone, he waited too long.
