An older person once told me during inclement weather - Do not dress simply for the walk from the house to the car, but rather if you have to walk home from where the car stopped.
Personally I tend to take a 9mm with the ability to function reliably over time with little to no maintenance and a couple extra magazines - for any shorter term rushed time away. Say family emergency pops up suddenly out of town, etc.
If it is an all out evacuation, like fire, hurricane, which could destroy residence, etc. - would take more, but that is a less likely to occur scenario for where I am. My family knows what to grab if that ever does occur, though. It is good to get lists made for what is important, and make sure each family member participates. You may be surprised by what some think is important, that you never thought of - and also what some might grab thinking it is important, when it is not.
I have a backpack or two that I keep filled with stuff that I use regularly, but even then, there are some items that are easily left in a car if necessary to go on foot. I am not young, and have no desire to expend what energy I have left toting more weight than what can be deemed absolutely necessary.
I have gone from a good smith revolver or 1911, to a beretta 92 or sig 226 to glock 19/26, and now tend to favor either a sig 320 m18 or 365xl.