Through and through shots are nice but it a] wastes a lot of energy b] has a LOT of energy that could cause way too much collateral
The Hornady XTP, Federal Fusion and Classic HP and Winchester 240 Platinum Tip are all hunting bullets...they will work great on 2-Legged vermin but there is a lot of recoil... I've run the Speer 210 Gold Dot, now called Deep Curl, HP and it expands well down into the 900s. The box of factory rounds I had ran 1180 from a 4". I only wish Speer would make a 180+- grain bullet constructed like the 200 grain .429 HP that is made to expand much quicker...then .41 shooters could have a SD load that didn't kick and still expanded...