I prefer a big, heavy, wide, flat meplat bullet in the .44 Special, from swaged 240 grainers to cast 250 grainers. I practically always use my own home-cast Lyman 429431 sized to .430".
If I am just shooting paper, the 250 gr. SWC over 4.1 grains of Bullseye or 5.5 grains of Unique both produce about 700 fps, a little less in a 3 inch or shorter barrel and a bit more in a 5 or 6 or 7-1/2 incher. An Accurate load you can shoot buckets full of all day, even in light alloy S&W's and Charter Arms Bulldogs.
My general field round for the .44 Special sixshooter uses the same Lyman 429421 SWC bullet over 7.5 grains of Unique. In 4 inch, 5 inch, 6-1/2 inch and 7-1/2 inch guns, I get anywhere from 900 to 985 fps.
The 7.5 Unique under a 250 SWC seems to be close to ideal for a general purpose revolover that may be belt carried for defense or woods bumming. I have no doubts at all I can take a large Rocky Mountain mule deer or a human antagonist under 75 yards with a 5, 6-1/2 inch S&W or 7-1/2 Colt New Frontier loaded with the Skeeter Skelton cartridge.
I have a large box of swaged lead hollowpoint SWC's made by a company called Albert's wearing a "Taurus" brand. I haven't seen them in a while but remember they weigh about 240 grains and have a soft alloy yet shoot pretty well under 1,000 fps. I have had them almost 30 years and know the maker went out of business about that long ago. With good case-bullet tension and a good, stiff crimp I think they may be great out of a M-296 for social use, and intend to try that out in my fiveshooter before I get too much older and more decrepit.
I tried out Elmer Keith's .44 Special load using 17.5 or 18.0 grains of H-2400 under my cast bullets, fired by standard large pistol primers, out of my N frame S&W and Colt Model P frame sixguns. They were very powerful and quite hard kicking in the lighter .44 Specials. The .44 Magnum was then available, stronger and heavier, and I began to use it as my high-velocity, heavy bullet big bore sixgun, going back to the 7.5 grain Unique load in the Specials. It's probably 95% or more of my .44 Special loading and shooting now.