WHAT IS THE BEST .22 LR AMMUNITION FOR SELF DEFENSE?

For a plethora of reasons which I don't care to debate, I now carry a S&W Model 317
as my Primary Personal Carry Weapon. Fully aware that a .22 LR is not the caliber
or choice for this purpose I at least want to have it loaded with the 8 rounds that will
do the most damage. I have read pro's and con's on hollow point verses round nose.
What I think I want is the heaviest & fastest round nose round available but don't
know what it would be. I would love your input. Please...no flaming me over my personal
decision to carry this weapon / caliber, as I said I have many reasons.