OMG stop with the 10mm is a 44 Mag if/when BS. The 10mm at its absolute best is the equivalent of a good 357 Magnum. That's it, that's all it's ever been and all it'll ever be. It's not in the 44 Mags neighborhood and never will be, hell it's not even in the 41 Mags neighborhood. Just stop already.

Amen, brother! A good .357 Magnum from a LONG barrel, maybe! Maybe you can do a 200 at 1150 FPS with a .357, but I’d think that’s about all. Certainly no sane 10mm ammo (that I would want to use in my guns) goes head-to-head with a .41 Magnum, much less a .44 Magnum.
These days the bear protection gun topic seems at the forefront with 10mm handgun discussions. I wonder about this stuff. I assume the points of 10mm-fascination for the bear people are: a lot of rounds in the gun, quicker follow-up shots, and enough power/penetration to get the bullet to the vital area (the brain).
I don’t live in bear country and I don’t pretend to know anything much about what actually stops a bear charge. I gather that none of the common handguns up to .44 Magnum are likely to reliably kill a big, determined bear
quickly enough with body shots to save you… ? So, as a practical matter, how many precision aimed shots you can reasonably expect to get at a bear (brain area) before he’s got you - with any type of powerful handgun? Is 15-16 rounds crucial? Six not enough? In actual shootings, what has happened with the 10? Do victims often run a revolver dry before it’s over?
I don’t know any of this stuff but I am tired of the “10mm is basically a .41 Magnum in an autoloader” jibber-jabber that’s gone on for years. Anyone who understands numbers can see that it is not. A decent, but perfectly safe, load in a 6-inch .41 Magnum will best the 10 by 10% in bullet weight AND at least 20% in velocity. “Enthusiastic” loads in the .41 will do even better. Numbers is numbers!
Apologies to the OP for the drift. I’ll be interested to see the P320 in 10mm when it shows up at the local gunshop. With thumb safety and a bit rougher grip texture, I hope!