While this tread started off talking about shooting these cartridges in a revolver it's had talk of them in semi-auto pistols also.
Potentially big differences, beyond the obvious type of actions.
I just wanted to make one point, a caution if you will, that all modern S&W N-frame cylinders are of the same diameter (~1.710" wide) though their lengths vary by model/caliber.
Since the .45 is the largest caliber N-frame its chambers uses the most available metal & being six-shots the cylinder lock notches are directly over the chambers which gives them the thinnest amount of metal thickness at the notch to support chamber pressure. An obvious weak point that pistols don't have.
My S&W 45ACP revolvers range from .026"-.030" thickness at the notch.
My S&W 44 MAG revolvers range from .039"-.041" thickness at the notch, which is a good 33% or more thicker.
The 44 MAG is a 36K psi max SAAMI cartridge with more metal at the weakest point.
The 460 Roland is a 40K psi cartridge with
less metal at the weakest point in a 45ACP cylinder. Less metal more pressure.
The caution in pistol barrels is whether they are fully supported, at the case's base/web area, or whether they are unsupported which makes them susceptible to case rupture, at that same point, when subjected to higher pressures.
My Colt 1911 Series 70's barrel (unsupported) can't handle the same power level of 45 Super loads, in S-L brass, that my S&W M4586's barrel (fully supported) can without bulging.
Just a heads-up on the differences, if you weren't already aware of them.
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