After reading the responses and talking to several seasoned loaders, we decided to test a few. BYW, the case dimensions for the Blank Brass and Standard Brass are exactly the same except the flash hole is larger on the Blank Cases. One Gentleman I talked to was very familiar with blank cases and said he had experience working with movie sets and theme parks such as Ghost Town etc. The earliest blank cases were designed with slightly larger primer pockets so reloading could be done by hand. On movie sets, apparently the primer was knocked out with a punch and a new primer could be seated with with a lot of handmade tools even with strong fingers. Then a dipper of black powder was poured in and was sealed up with wax or glue to keep the powder in. Later when hand priming tools became common, the holes were made closer to standard to eliminate the backing out problem. Sounded like he knew what he was talking about. I decided to try a few with light loads to start. Using around 5.5gr of Trail Boss with a 240gr lead bullet. Primers fit snug, but maybe just enough less resistance in seating to notice. Loads shot fine with zero problems with primers backing out. Shot 50 rounds in 3 different revolvers and saw no difference in any of the guns. Moved up to a load of 6.5gr of 231 which is my normal target 45 Colt load and as of yet, have seen no difference at all compared to standard cases. I've loaded several cases 5 times with several different brands of primers. I have not run any through a chronograph but don't intend to. These are everyday target loads and I expect they are running around 800fps out of a 4" barrel. No change in POI in either case, so I'm planning on loading up the cases I have since once fired 45 Colt brass is bringing $1.00 or more per case on the big auction site. Not scientific testing by any means but just my experience. Thanks to all that chimed in and welcome all comments