I have a M&P 2.0 45 with 4.6” barrel. I’m wanting an OWB holster and I have a Crimson Trace CMR-206 for it.
The CT CMR-206 is the real holster compatibility impediment. You could do a Google search for CMR-206 holster and go from there.
Honestly though, I'd prefer to push you into getting a Surefire or Streamlight instead of the CT.
I do own handguns with lasers, have drawn one in self defense with the laser, and I'd argue that generally speaking, a light is far more useful, especially a blinding bright light.
A Streamlight TLR-1 HL or a Surefire X300 are 1,000 lumens, which is completely blinding to anyone on the receiving end. Inherently there's a tactical advantage with that.
Safariland makes a superior OWB holster in my opinion and has options for your gun and a TLR-1 or X300. Their ALS system is second to none.
If you have time to activate a laser, then you have time to get your front sight on target. Having light to positively ID a threat, and enough light to control their ability to see is extremely advantageous.
During daylight hours, a laser, even a green laser, can be hard to see on target, depending on the color of clothing the attacker is wearing.