The 4506-1...
-Doesn't have the "step" on the frame, by the dust cover (as with the 4506 & 645). So it's thicker in that area.
-Has a slightly thicker slide than the no-dash 4506 & 645, and eliminates the "rib" at the top of the slide found on the 4506 and 645.
-It has a round trigger guard (though I think some early 4506-1s may have had hooked trigger guards?)
-Denzel Washington carried two of them in Training Day and took the 4506-1's inherent baddassery to astronomical levels; this cannot be said of the no-dash 4506.
As was described, the 4506-1 is basically a 10mm pistol. In other words, they took the 4506/645 platform, beefed it up to handle 10mm, and didn't bother making a less-beefy version for .45. The 4506 (no dash) and 645 are more or less the same, in terms of the frame/slide (though, of course, the grips, sights and other internal things are different).
I'd love to have a 4506-1. But my 645 gets the job done.
I was in my early 20s. Back then, the P220 was imported by Browning and marketed as the BDA. It was seen as a bit exotic for the time and spendy.
I believe there were also some changes made to the slide rails, but I think this was done for ease of machining and standardization across the model line. I don't think you can use the slide from a "no-dash" on a "dash-one" model, except for possibly a few of the transitional 4506 to 4506-1 models. Someone else here may know more.
I learned this when I purchased a slide and barrel from a 4516 for use on my 4506. The first top end I tried was from a 4506-1, and while it did mount up to the rails on my 4506 it was mismatched as far as the slide stop and internals were concerned, making it non-functional. I had to use a slide specifically from a 4516 "no dash" on my 4506 "no dash" and it functions perfectly.
(In case you wanted to know, a 4506 lower with a 4516 upper makes what is essentially a 4596.)
Unfortunately, it has zero information on part numbers for the 4505. I should then be looking for a 1992 handgun parts and accessories book?