I will attest to the possibility of handloading error, I was in a hurry to get some rounds ready for shooting the next day. At that time I was crazy about using a sonic cleaner on my brass, I sonic cleaned a load of 32-20 brass and the next morning loaded up 50 rounds to shoot at the range. I did not immediately notice any difference in the rounds and was banging away at a fairly regular pace, single action as is my usual preference. I was into the third or fourth cylinder full when the hammer dropped and instead of a solid bang I got a pop, I recocked the hammer and then thought to myself...that was wierd. I lowered the hammer, opened the cylinder, unloaded and placed a thumbnail under the forcing cone looked down the barrel...dark, hmmmmm. That was my first squib load and the nearest I can figure was either caused by there still be some residual moisture left in that case which spoiled the powder or lack of powder...I have since gotten back in to the good habit of double checking to see if all cases have equal amounts of powder.