Thanks for the replys. I have taken several deer with my Super Blackhawk using Remington 180 grains JHPs at 30 yards and closer with out any problems. That said all the shots have been at broadside deer keeping away from the shoulder and any quartering shots. I have also taken a couple of deer with a 357 magnum. I know with a pistol shot placement and penetration are everything. My Hornady manual recommends either Blue Dot or W296 with their 240 grain XTPs. I have load books for Hornady, Nosler, Sierra, Speer,and Accurate to choose from. I am interested in what your experiences are with the loads you hunt whitetails with. We have a wide range of deer here in Missouri. If I hunt Northern Missouri most of the bucks I see are in the 185-225 lb range. I have been hunting the middle of the state lately where the deer average 125-200 lbs with most being in the 150lb range.
Smith Crazy: I really like Accurate powder and load it in 9mm 28 special, 40, 45, and 44 mag. I hear quite a bit about H110 and W296 and while I don't have any of that powder on hand I would like to load some rounds with those powders also to see how she likes them. Thanks again for all your replies!