Every firearm is different, been casting/reloading for the 44spl & mag for 30+ years. Owned lever actions, multiple 44mag bbl's for contenders, multiple black hawks, multiple ca bulldogs, s&w 44spl's and 44mags (624's/29's/629's).
The lever actions, contenders & black hawks tended to be more accurate with the heavier fn cast bullet designs (260gr+).
The s&w revolvers tended to be more accurate with cast bullets in the 220gr to 260gr swc's and type III wc's.
The ca bulldogs preferred the 180gr to 220gr cast bullets.
180 & 200gr fn's left (ca bulldog) and 260gr fn hp's (the 640 mp mold from above post) right
Never could get that 640 series bullet (pictured above on right) to shoot in a 629-3. But I tossed a reddot on a 10" contender bbl/44mag and sighted it in at 100yds to bang on steel.
That chicken scrath of a target doesn't look like much. I was moving the dot around on the top 3 target. Got it close and moved to the bottom 2 targets. Shot the left target and dimed the dot down 1 setting and shot the bottom right target.
Gave the dot a couple clicks down and 1 click right and beat the heck out of the 6" steel @100yds.
It's hard to beat the "keith" style swc's in the s&w revolvers. I use a mp mold (432-256) for my s&w revolver needs anymore. The 4-cavity mold casts a 260gr solid nose/252gr small round hp/245gr large round hp/238gr penta point hp.