There are very few powders that react badly that we use, for the most part, if we have just a hint less than what is 'The Norm"...however, I've seen were some try to reverse this thought! Now that's dumb!
Knew a fella some years ago that would not listen to ANY oldtime reloader and he insisted that he knew what he was doing....famous last words...he "knew" that if he loaded mag loads in a spl case it was just all fine and dandy...This idiot destroyed a hand built fully engraved Colt SSA in .44Spl with a very hot mag load of powder crushed into a spl case! He was unharmed, but his weapon was trashed. He asked me to rebuild it for him. I instructed him the closest directions toward the gates of hades...I don't associate with morons that have firearms!
Thank goodness we have good folks here that use their heads and understand safe practice...That's why I like it here. Our folks LOOK way ahead before they ever think of a leap into the unknown. Good on all of ya'll!
Wade