Thanks for the replies. New to reloading, don't cast my own. I'm looking for something suitable for javelina through black bear, more often as a back up to a long gun. For example, when turkey hunting a couple of months ago we stumbled on a bear and I had a tag. Fortunately I had my 681 with me, and the bear is being made into a rug as we speak. I've been planning to set a .44 mag, but may have a steal of a deal in the works for a Model 25, that's why I ask. Local powder availability has been a little hit or miss, but of the powders that seem likely candidates, 2400 is usuallly in stock. Primers, on the other hand..........