If you have any slop in a cylinder you will have accuracy issues. If you are wanting a carry gun and at those ranges it won't make a difference.
But since you said you are going to use it for a range gun. Don't you want to see how good you can shoot? Having 45acp's that are looser in the chamber than the 45 colt you will have accuracy issues. I have read that reaming the throats of a 45 colt cylinder makes the difference between 2" or 6" groups. I have not had those problems with my 45 colt. But just imagine the throat issue in nothing compared to using 45 acps in a 45 colt chamber. If you get a 625 that is a 45 acp revolver there are things that you check to get acceptable accuracy out of it. 45 acp cylinders have a step in the chamber for the case to head space on. That is very important in getting any kind of accuracy.
The bullet has to have a straight shot at the forcing cone and barrel to be accurate. The barrel will not solve the problem of long throats or loose chambers.
Finally, Cowboy action loads in 45 colt are much lighter than 45 acp loads given the same weight bullet.
Your gun, do what you please, BUT you asked and we are giving our opinions. My opinion is you are doing irreversable conversion to your gun and will gain nothing by doing it with Cowboy action loads availible.
John
But since you said you are going to use it for a range gun. Don't you want to see how good you can shoot? Having 45acp's that are looser in the chamber than the 45 colt you will have accuracy issues. I have read that reaming the throats of a 45 colt cylinder makes the difference between 2" or 6" groups. I have not had those problems with my 45 colt. But just imagine the throat issue in nothing compared to using 45 acps in a 45 colt chamber. If you get a 625 that is a 45 acp revolver there are things that you check to get acceptable accuracy out of it. 45 acp cylinders have a step in the chamber for the case to head space on. That is very important in getting any kind of accuracy.
The bullet has to have a straight shot at the forcing cone and barrel to be accurate. The barrel will not solve the problem of long throats or loose chambers.
Finally, Cowboy action loads in 45 colt are much lighter than 45 acp loads given the same weight bullet.
Your gun, do what you please, BUT you asked and we are giving our opinions. My opinion is you are doing irreversable conversion to your gun and will gain nothing by doing it with Cowboy action loads availible.
John