To be the voice of "dissent" I run quite a lot of Airsoft stuff on my 15-22. My 15-22 is babied much more than my Airsoft stuff ever was. Anything that will break good quality Airsoft components will break a 15-22.
There are good and bad quality Airsoft components though. At my local Airsoft shop they have a scope I am dying for (Spectre). Nice clear glass, nice sharp lines, but the guy behind the counter refuses to sell it to me because he knows what I want to do with it and he won't even sell it to customers to put on a GBB Airsoft gun because the vibration of them firing will damage the sight.
I have used various Chinese no name brand and some brand names (Like NC Star and Tru-Glo). A decent enough Airsoft scope will work for the 15-22. Because I like playing dress up with my 15-22 I have owned a couple of red dot, a couple of holo style sights and a couple of magnified optics. The ONLY scope I have had issues with was a real-steel budget scope. I ran out of elevation on it.
For decent budget grade stuff I'd happily look at the NC Star range. Which is a far cry from what I was saying a couple of years ago!
No name H1 look-alike in "La Rue" mount. Worked great. Reduced battery life but no other issues:
Another setup I tried:
NC Star holo style projector:
Current setup, the NC Star SRT
The real world scope which gave issues.
Edit, I still have these scopes, none were replaced due to failure, except the real steel one. They were replaced due to playing Barbie. The Airsoft stuff is back on my Airsoft guns.