One of the first centerfire rifles I ever bought was an Interarms X in .243 and it was good for any i needed to kill here in Indiana. Sub 1" groups out of it with about any ammo i put through it which was outstanding considering it had a sporter barrel on it.
My first centerfire rifle was an Interarms Mk X in .243 Win. It was a great rifle for mule deer out to about 350-400 yards and white tail deer and antelope out to about 450-500 yards. Mine also shot sub MOA 5 shot groups. My dad had a Rem 700 in .243 Win and and we would shoot head to on prairie dogs out to about 400 yards with 70 grain bullets loaded to about 3600 fps.
It's one of the few rifles I've sold. I don't recall why I let myself be talked out of it, but I've always regretted it.
That's actually quite close to what NATO wanted after WW2, a .250 or .260 cartridge.
But the ISA forced 7.62x51 on them, then switched to 5.56.
The .280 British was the original cartridge that the FN FAL / L1A1 was originally developed around. It was an intermediate power round, developed for both optimum terminal ballistics using an FMJ bullet, and reduced recoil to facilitate controllable fire in a select fire assault rifle.
However, the US military held a lot of sway in the post WWII arena. The US ordinance folks first insisted that the cartridge be able to be manufactured to the maximum extent possible with existing tooling. In response the British modified the round to use the same head diameter and base dimensions as the .30-06 and called it the .280/30.
The .280/30 was also rejected by the US as what the fossils in charge really wanted was a full power battle rifle cartridge, one that was slightly shorter to provide greater reliability in a select fire battle rifle. They totally missed the lessons learned in WWII that:
1. Combat most often occurred at ranges around 100 yards and rarely ever occured at ranges greater than 300 yards, making a full power round unnecessary; and
2. Controllable fire in a reasonable weight rifle (as opposed to something like the BAR) required a lower recoil intermediate power round.
The end result was the 7.62x51 NATO, with .30-06 (of the time) performance in a half inch shorter case. The FAL / L1A1 had to be redesigned to accomodate the larger round and was never really practical to use in full auto mode due to difficulty in controlling the recoil. The M14 suffered the same problem and was rarely issued, let alone used with the full auto sear and selector installed.
To add insult to injury, by the time the 7.62x51 NATO round was adopted and forced down NATO country throats by the US, the US was already developing an intermediate power .22 caliber cartridge and exploring a lighter weight assault rifle to fire it.
The original 5.56x45 NATO, 55 gr M193 round wasn't a bad round, all things considered (I liked it in the issued M16A1), but the things that made it effective were neutered first in the heavier and slower 62 gr SS109 rounds used in M855 ammo, and then neutered even further in the 14.7" M4 barrel, reducing the range at which it would tumble and fragment from around 200 meters with the M16/M193 combo to around 50 meters in the M4/M855 combo.
The ultimate irony is that 63 years after sticking NATO with the 7.62x51, the US is now exploring a more effective round, and candidates like the 6.8 SPC, and 6.5 Grendel offer intermediate performance similar to the original .280 British:
.280 British, 140 gr FMJ, .284" diameter bullet at 2,550 fps.
6.5 Grendel, 120 gr FMJ, .264" diameter bullet at 2,700 fps.
6.8 SPC, 115 gr FMJ, .277" diameter bullet at 2,575 fps,
The British selected the .276" land diameter/.284" groove diameter bullet very intentionally after exploring the effects of Hague Convention compliant FMJ bullets yawing, tumbling and fragmenting after impact. They found the effect was maximized with the .284" groove diameter bullet.
Many people think that the tumbling bullet thing came along with the development and adoption of the 5.56mm NATO, but in fact the US Ordinance boards used it as a justification to replace the .45-70 when they introduced the .30 US (.30-40 Krag) round in the M1892 Springfield.
I always thought a great combat rifle would be an M-14 scaled down to .243 size. The company I use to work for had a 1500 acre deer hunting lease near Lampasas, TX and most of the guys from work used .243's and the most popular rifle was a Browning lever action. I once saw a turkey running at 150 yards and the guy standing next to me made it explode with his BLR .243 and almost everyone I've ever known who used a .243 was a really good shot!
The .243 is arguably a bit much for an intermediate round, but it's an excellent dual purpose varmint and medium game round with the standard 1-10" twist barrel. 85 to 100 gr spire points are available with decent BCs and good point blank ranges. Lighter bullets from 75 down to 55 grains make excellent varmint rounds.
However, in a faster 1-7" or 1-8 twist barrel the newer, heavier VLD bullets like the 115 gr VLD turn the .243 Win into an excellent long range cartridge. It can launch a 115 gr Berger VLD at 2800 fps and it'll stay supersonic to 1345 yards. At 1000 yards it drops 30 1/2 MOA from a 100 yard zero and only drifts 7.5 MOA in a full value 10 kt cross wind.
In comparison a 6.5 Creedmoor. 140 gr ELD at 2710 fps drops 30 MOA and drift 6 1/2 MOA at the same 1000 yard range in the same wind.
The 6mm Creedmoor will launch a 108 gr Berger at 2960 fps, staying supersonic to just over 1400 yards and dropping 27 MOA at 1000 yards with 7 MOA of drift.
The .243 win launches the same 108 gr bullet slightly slower at 2890 fps, it'll still stay supersonic to 1375 yards and drop 28 3/4 MOA at 1000 yards with only 7 1/2 MOA of drift.
In short it's not the latest and greatest long range bullet but with the right twist in the barrel it will still give you superb long range performance and gives up very little to the 6 CM and 6.5 CM.