YUP!
I have had both L/H AND R/H come loose. When they do, I use that opportunity to fully unscrew them and take all the parts out, clean the threads and springs with Remoil, clean the inside of the cylinder hole, and reassemble. I have not found the need to use any type of thread locker, just put a piece of leather around the ejector rod before using a pair of pliers to tighten everything up. VERY IMPORTANT!!! MAKE SURE YOU HAVE EMPTY CARTRIDGES IN THE CHAMBERS WHILE TIGHTENING EVERYTHING UP. This will keep everything aligned under the pressure of tightening. Don't "Gorilla tighten" it, just a bit past snug will do.
chief38