My experience with CFE223 & my M&P10
In answer to your question:
Yes, I am currently in the process of attempting to use CFE223 to work-up a load for my Big Ten. However, I'm not having much luck so far. Have dropped all the way down to 46.2gr with Win. Brass, WLR Primers, and 165gr Hornady BTSP bullets. Also dropped down to 49.2gr using same brass, primers and Hornady 150gr BTSP. Both these loads are way down the chart of the Hodgdon data, but I'm getting significant case head swipes and visible signs of ejector marks. I plan to go back down to the starting levels of 45.4gr with 165gr and 48.4gr with the 150gr bullets and see what happens. I'm convinced that my bolt is trying to open up too soon and creating the situation. I've read a lot on this and it seems that many many people are finding that they are getting similar results with the CFE223. At this time, I couldn't recommend it for use in an M&P10. However, I may be able to change a few things and get it to work. If you try it, let us know how it goes for you. I foolishly bought a couple of kegs of the stuff based upon availability & the recommendation of a buddy of mine.