I just went through all of this! I have on press dispensers of different manufacturers, mostly Lee and Hornady, finally made the decision to go to an automatic powder dispenser "off press" for rifle and my 460S&W. Why? Because the Lee Pro disk works great for pistol(up to 44mag), but if you try the "double disk" for larger amounts of powder...it is awful! Powder leaks all over the place! I have the Lee Auto Drums, and some work, some don't, I blame it on the plastic parts! The Dillon powder measures are okay, but I had to spend more money on an expensive item to begin with to have a prayer at determining a consistent load, there are ZERO markings on the knob used to adjust powder and I needed a way to go up or down in small increments. At around $75 for the powder drop then another $15 for a knob...well, I bought 2 setups and figured there has to be a better way. So started looking at the automatic powder measures. I looked at them ALL pro's and cons and ended up with the RCBS Chargemaster combo. Normally these things are around $300+ dollars and is the most expensive one (of course) I saw available, so read a bunch of articles and comparison videos on you tube, accuracy of your measurement is #1 but you also need to make sure that emptying the machine is easy, and a lot of other little things, like being able to program loads into it (I load for about 20 different calibers). In the end I chose the Chargemaster, found it for around $250 on Natchezz(2 weeks ago) and couldn't be happier. First load was 51gr's of H110 for my S&W XVR in 460...I compared it's displayed weight with my RCBS 10-10 beam scale and it was right on. So if you are going to spend the money do the research and make your decision...I will tell you that when ever a comparison is done, with ANY of the other auto-powder dispensers, the RCBS Chargemaster Combo (make sure you get the combo) won decisively.
Good luck with the search!