I have a powder measure that I use for pistol loading. Been using Bullseye since about 1972 and bought the measure in about 1975.
Initially, I did a calibration curve for the measure. Every time I load I go back to the initial setting, and every time its right on. I can't tell you how many different batches of powder I have used in the last 45+ years.
All I can say, thus, is that the density of the powder has not changed. I don't measure chrono data, so I can't say there.
OTOH, current Unique settings change from time to time.