If you want a frugal 'big bore', at least as big as the .460, consider a 625 in .45 ACP. Then - ammo-less on a Sunday, you can always get ammo at WallyWorld, etc. Of course, if you reload, you can load .45 Auto Rim brass with .45 Colt lead, like the 255gr LRNFP/255gr LSWC/250gr GDJHP. To pop around, you cannot beat 230gr FMJ ball ammo in moonclips. The currently available new 625JM is a complete package for such.
Now, if you really like .45 Colt, find a 25/625 Mountain Gun. Beautiful balance - traditional short lugged/tapered barrel (4") look - and .45 Colts are mild enough for wood grips. Fun gun - and my first ever S&W over seven years ago. I liked it so much, I bought a second one to take up some of the duties from my sentimental valued original one. In fact, it's in my range bag now - just in case I get a chance for a range trip today.
Of course, if you want the 'biggest/baddest', just get a 4-6.5" .500 Magnum. A cylinderful per range trip will put a smile on your face... and empty the adjacent stalls at the range, too. Another plus, if you are attacked by a wayward waterbuffalo or rabid 18-wheeler, you'll be prepared.
Stainz