I'm thinking we're talking working guns vs hobby guns. I don't remove the cylinder every time I do some light shooting now days, especially if shooting jacketed ammo. I'm retired! When I did extensive shooting with Dept supplied ammo at practice sessions, training sessions or qualifications, it was generally done with the cheapest of cast or even swagged ammo. When I used my own ammo it was my pure wheel weight castings with soft alox/beeswax applied with my lubrisizer. Yeah, the cylinder came off every time. In those conditions I don't see how you can properly clean a revolver without removing the cylinder.
With a working gun shooting lead I don't see how you can properly clean one without removing the cylinder. Heck, after practice, training or qualifications, even our hands were getting black. It would take great effort to get the lead, carbon and burnt lube out of the cylinders and off the face and out of the barrel and frame window. I also don't recall anyone being overly concerned about the screw heads or light scratches.
Some of the comments saying remove the cylinder to clean internally only when it starts getting sluggish or stiff, a working gun? Really? It may be too late then!
Occasional shooting using jacketed bullets? Yeah I get that. But then you miss out on the aroma of the beeswax based lube (mixed with lead).