It is difficult to assess, because so much is dependent on what you are loading, how much you shoot, and whether you will be buying components in bulk locally or or have to incur additional costs to have them shipped. Your initial equipment costs, upgrades and accessories, and time will factor in too.
However, aside from the fact that you *will* tend to shoot a lot more, you will likely save a moderate amount to a bunch over factory ammo.
Or not, as in the case of cheap discount shotshells these days vis-a-vis the cost of premium components for handloads. And casting your own bullets, while it can save you a bunch in the long run, esp. for unusual or expensive boutique caster bullets, is fairly time intensive.