I am totally immune to novacaine and xylociane (both spelled wrong!) My brother has about 15 minutes from a triple shot of xylociane. Both of our children get a small amount of relief from both. Non cocaine based pain meds work fine.
I have had several teeth pulled and 2 bones set without any local or general sedative. I had a Rx for oxycodone from wisdom tooth removal, I burnt the Rx and took Advil for a day and a half.
BTW, a former employee and sometime drug dealer, told me not to waste my money on cocaine.
My wife doesn't have my abilities to not feel pain she just ignores it. $ kids/no meds. About 5 years ago her appendix exploded, after surgery by a day I was sitting with friends in her hospital room and a nurse comes in and about pain (From 1 to 10) My wife responds in a calm voice "10". The nurse was skeptical, one of the friends who is a physical therapist for the hospital, told the nurse not to let the calm demeanor fool her. My wife feels pain, she just refuses to let it control her! (we refer to her as a Vulcan with round ears!)
Ivan