If you remove the trigger w/hand and cylinder stop (or just the c/stop spring & plunger actually) , the cylinder will spin freely.
You can carefully wedge a small piece of wood gently between the extractor rod and the housing to hold it in position and rock the cylinder to see if the rod turns (loose rod).
If it's loose,,tighten it up as best you can and see if that will allow the cylinder latch to open the gun.
If the forward locking bolt is stuck for some reason, some oil into where you can get at it both in front of the ejector rod and in the joint of the 3rd lock.
About the only place you can get at the locking bolt is right in front of the ejector rod ,,and not very securely.
You can see if it moves forward at that point by pressing it in that direction very carefully with the tip of a small screwdriver.
You may be able to move it forward enough to unlatch the cylinder.
If nothing moves,,you can disassemble the forward locking bolt from the underside of the bbl by removing the 2 small pins in the shroud.
One holds the bolt spring and plunger in place. The other the small cover.
With the bolt out, the center pin pushed all the way forward from the back inside of the frame, the cylinder is free to open.
FWIW
If you take the cylinder assembly apart, it's not the same inside as other S&W's. The TL has a couple different components inside,, a small C spring and a collar.
The C spring snaps into a groove in the center pin.
The disassembly is a bit different in that the extractor rod head itself has to come off first (RH thread),,then slide the crane off. Push the center pin forward, remove the C spring and pull the collar and a small coil spring off the pin. Then slide the pin backwards and out of the cylinder.
The extractor rod is still in place. Remove (RH thread,,this may be your problem part above as well as the extractor rod head itself).
The extractor lifts off the back of the cylinder.
Don't loose that tiny C spring!