Way back in 1966 I bought a Browning T bolt 22. It was beautiful (still is) and great (shoots the best groups I've ever managed.) The shop I bought it from suggested I buy and shoot Remington ammo. So I worked some OT and loaded up. For whatever reason, it has been the most accurate I've used. Of course I still have some of the ammo, but its now my accuracy standard (Hi Velocity hollow points, no less.) I don't discard the idea I might be able to find high dollar match ammo that might be better, but not much, and why? Yes, some of the stuff still has its "Klein's" price tags at 66 Cents.

I've not had a misfire that I can remember, and I probably would if I'd have one.
I've bought a lot of 22 caliber ammo over the years. I've bought more Remington, Winchester, Winchester white box, CCI, and a host of others. I still like Federal ammo because it seems to go bang when I want it to. Rifle, shotgun, and handgun.
But long ago I adopted a method to figure out why a round doesn't go off. My range bag (or my jeep, just a big steel bag) has 2 pairs of pliers. I give every round a second chance. I turn it 90 degrees and give it another hit. But when I get a cartridge with 2 dead strikes, out comes the pliers. You just grip the case with one set and the bullet with the other and bend. Out comes the bullet. If you turn the case upside down, all the little flakes of powder will fall out on the grass, fertilizing it. Then look inside the case. You should see a ring of colored priming compound spun into the rim. What I think you'll discover is almost all the genuine ammo caused misfires are caused by lack of compound.
But in the situation with the OP here, I can't imagine 50% failure rate. I'd guess its the gun. Yes, try Federal or CCI and see if you have the same or similar results. When you do, it could be the mainspring not being properly tensioned, or dirt. The dirt can be in the firing pin channel, or the cylinder. Make sure the cartridges seat fully in the cylinder. Just a little grit or carbon build up can cushion the firing pin blow.
If the tension screw is fully tightened, find a piece of metal and shim where the screw pushes against the mainspring. A fired 22 case will work after you've stepped on it. Its not a permanent fix, but it should hold for a few rounds. Its like making the screw longer.