I don't have the 41 or 46, so I cannot speak for them.
I do have a Ruger Mark I & II as well as a Browning Buckmark. The Buckmark is much smoother than the Rugers.
I was at the range with the Buckmark. The guy next to me was shooting a Ruger. I let him shoot a round with my Buckmark and almost didn't get it back.
As far as I know a M46 is just a Plain Jane version of the M41. If you can get it for $300 (about 1/5 the cost of a new M41) GRAB IT! Especially if it functions well with all types of ammo tried - that's a bonus right there!
For what it's worth on the Ruger and Buckmark:
we had Ruger Mk4's in the past as club guns and got rid of them because they were unreliable as a club gun. It is somewhat of a standing joke at our club to wish anyone with a Roger "good luck" before they shoot in a comp' because we continue to see so many DNF's with them.
At my previous club the club records showed that the Browning Buckmark (in various formats) was THE most popular .22 gun amongst members of the club......
I don't know anything about the S&W M46 but I absolutely love my M41.
Another very reliable and accurate .22 that you might like to look at is the Beretta 87 Target. I have one and I am amazed at its reliability and accuracy.
My only gripe with it is the length of the grip, with the magazine actually making up a part of the length of the grip. I have somewhat larger hands (the S&W M41 is perfect for my grip) and the Beretta 87 grip is perfectly functional and adequately comfortable but for me is just that little bit too short for me to be entirely happy with it.