I'm still trying to figure it out myself. They all have something to like but typically something not to like.
The factory boot grips are a little too small for me so I wrap 3-4 rubber band around the grip. Surprisingly they lock in pretty good.
The hogue tamers I've tried lock in even better and are still good for carrying on the belt. However, on the centennial models the tamers put my hand in the spot to draw blood on my thumb from the takedown lever / thumbpiece.
I have a gun with an exposed hammer now (637) and I want to try the tamers on that gun. It might not cause the thumb gouging because your hand sits a little lower on the grip frame.
A nice gentleman on here sent me some Uncle Mike Combat type grips and they feel really really good. However. When I was dry firing with them yesterday they don't seem to lock in as well as the boot grips for some reason. They feel really good and they are consistent on the draw for me. But for some reason I just don't feel like the gun is locking in on a 2 handed hold as well as I want.
I'd like to try the Hogue bantams some day but I mainly carry AIWB so they don't necessarily have to be that small. And the bigger grips give more control during recoil.
I have a set of Pachmyr Compacs and they feel good, and lock in really really well. But for some reason I didn't shoot well with them on the first time I tried. I need to try again. However, they're about as thick as J frame grips go and for me not the best choice for carrying. Plus the rubber is so tacky your clothes stick to them.
It's going to be very subjective though. Everyone's hands are different and what might work for me might not for you.