This can also be a symptom of end shake on the cylinder or yoke. Even a small amount of further intrusion by the end of the ejector rod on the locking bolt can cause the gun to be more difficult to open.
Also check that the eject. rod itself is straight, and that it, and the locking bolt were fit correctly. If you remove the cyl from the yoke and press it on a flat surface ratchet side down, the center pin should come up flush or just slightly (.010) above the end of the ejector rod. Fit this way, the rod and cyl assy will "cam" off of the end of the locking lug properly. The assembly may not have been fit properly in the first place. These are not drop in parts, and for me this is one of the most difficult areas of the cylinder assembly....or "strap up" as the factory calls it....to get right.