This is my opinion only. If I were to use an AR-15 for interior home defense, I'd want every unfair advantage at my disposal. I want to have the option of different sights. I want to be able to overcome low light/no light & blind the intruder. I want to protect my own hearing.
1. Red dot optic or holographic optic.
2. If I have a fixed A2 front sight post, I'll equip a folding rear back up iron sight. If I have an AR equipped with a full length railed handguard, then I'll equip 45° off set iron sights. If the optic fails, I can go to back ups.
3. A rifle mounted LED light. Continuous, momentary, pressure pad, whatever works.
4. If I have a railed fore end, I'll equip a laser.
5. If I lived in a free state, a suppressor. Because I don't, I have a pair of electronic muffs in the bed stand.
While I would like to use an AR-15 for interior home defense, within the close confines of my typical suburban home, a semi-auto pistol equipped with night sights, light, & laser is my best option.
I can clear the corners and interior space of my home using a pistol faster and easier than with a long gun. I also have the option to operate a pistol one handed, leaving the other free to move family members, children, operate a telephone to call 9-1-1, etc.