I use OT bullets in place of jacketed for magnum rounds. I shoot them in revolvers and carbines of the same caliber. I get no leading in carbines at 1600 to 1800 fps. The SWC style cuts clean holes and the RNFP feed perfectly in lever guns. I don't bother with target rounds, as a rule. I practice shooting close to what I carry. I'm even using them for .45 ACP. The feed well, don't lead, and cost much less than FMJ or Jacketed HP bullets.
I've heard they work in Glocks and H&K too, which have polygonal rifling. I can't say because I don't own one.