You are "Mixing metaphors" as it were. Winchester Large Pistol are listed for standard or magnum loads as Winchester only makes the one Large primer. This is not the case with their Small Pistol primers.
For all practical purposes any small sized primer can be used in any handgun cartridge that uses small primers. This includes Small Pistol, Small Pistol Magnum, AND Small Rifle, either standard, magnum or match makes no significant difference. The exception would be when loading absolute maximum loads in high-intensity cartridges such as .357 Magnum, 9mm +P, .40 S&W, and similar cartridges.
And before some (inevitably) jumps in and says you will get mis-fires, FTFs with small rifle primers in handguns, this is simply not true! I have fired literally thousands of rounds of re-loaded ammunition using small rifle primers in both revolvers and semi-automatic pistols over many years and have had exactly zero FTFs from this or any other cause that cannot be specifically identified!
What you will see, but only if you chronograph your loads, is one primer or another can give better (lower) extreme spreads, standard deviation, and a small change in velocity for the load. Accuracy may be better with one primer or the other, but this is true depending on manufacturer too.
Short answer, YES. There is no safety issue except as mentioned above.