I lusted for one about 10 years back. As I recall , folks on another major dedicated "Central Rimfire Forum " were complaining of excessive fouling and marginal accuracy in the 17 cal single six's. I ended up backing off.
That may/may not have been cured by now in current production guns but have to agree that I've had fouling issues in every 22 mag ( parent cartridge to the 17 HMR) chambered handgun I've owned.
I'd google ( the bracketed words above) to find those discussions again.
Let us know what you find if you take the plunge.