Jimmy, that is a question I'm pondering right now, too. I have thought about carrying the BB gas-checked 158 grain soft lead swc "heavy +p" that I carry in my j-frames. The problem there is that, according to BB's info, I would be giving up a good bit of velocity and energy that I would have in my 3" Model 36-1. Why carry a heavier, bulkier sidearm and give up that advantage? I have thought about ordering some of the BB "Tactical low flash etc" .357, but there just isn't that much advantage over the "heavy .38 special +p" ammo, and that would be another expensive specialty round to buy.
To answer your question, right now my 2.5" Model 19 is loaded with a 6.4 grain Unique/158 grain GA Arms 158 grain swc handload. I haven't had the opportunity to really wring that load out, but it seems to have very acceptable "combat accuracy" from the short barrel.