Actually, I mostly practice shooting without using the sights. I know that in a self defense situation, I won't be taking the time to squint at the tiny little sights for slow fire target shooting but instead it'll be point and shoot.
I do have a laser on my snubby but that's more for dry fire practice and trigger control. Well, it is kinda fun drilling holes with a red dot at the range.
I do also use the sights for slow fire target shooting and I've outshot my buddy who was shooting his .45 Springfield Tactical at 25 yards.