Be extra careful with them as there is no trigger to hold the hammer at half cock for loading and unloading,,and no 1/4 cock to catch the hammer should it slip unexpectedly while loading/unloading.
Hammer position has to be held by one hand, approximating the correct point of hammer 1/2 cock while you load.
Sooner or later while slipping rounds into the cylinder, replenishing one or two emptys while leaving the other live ones in there, turning the cylinder to correctly index it ,,etc,,that hammer held back by your hand and nothing to catch it if it falls unexpectedly will result in a suprise.
Maybe that's why the guy I knew who had the Ruger set up that way used to take the cylinder right out for loading/unloading. You still could get an unexpected firing setting it back in place though.
Interesting concept though. I think some guy named McGivern used to give a demonstration using a Colt SAA shot in slip-gun style.
There was a Colt SAA floating around the local shows for years converted to .22rf and slip-gun use by Alonzo Crull (sp?).
Short bbl, no ejector rod, altered hammer, etc. The guy wanted to pay off his mortgage I think with the sale of it (recalling his price) and it was always around. Maybe somebody else finally owns it now as I don't think I've seen it in a couple of years now.