Dish, you’re going to have good luck with that projectile with #9, 2400, and H110. I have Specials for special velocities. I assume you want Magnums. My revolvers, which are 4 different configuration 629-4s, a SBH 7.5 inch and a couple of Anacondas, are not picky every one will shoot a good jacked bullet into the occasional 1.75 inch group at 25 heard.
But, my Ruger No.1 with a scope, and my Miroku with a Lyman 66 LA at 100 yards prefer 2400. I’m going to experiment with Magnum primers with 2400 to see if I can get a more complete burn.
You have a great gun and great bullets. The real answer is How much recoil is too much?
And yes, shoot some water filled containers. Good fun!