SLOBBER ALERT! 
It is widely known I'm a 57 fanatic and a devotee of the Ruger Blackhawk in .41. The cartridge is the same and I handload a lot of them.
210-grain Nosler JHP over 19.9 grs of H110 and a CCI mag primer
210-grain Sierra JHP (ditto)
Very accurate and they don't pound your hand.
Now, I've also run the Speer 210 Gold Dot over H110 and 2400 and they do quite well.
Likewise the 210-grain Hornady JHP is a good bullet.
Go forth and shoot!

It is widely known I'm a 57 fanatic and a devotee of the Ruger Blackhawk in .41. The cartridge is the same and I handload a lot of them.
210-grain Nosler JHP over 19.9 grs of H110 and a CCI mag primer
210-grain Sierra JHP (ditto)
Very accurate and they don't pound your hand.
Now, I've also run the Speer 210 Gold Dot over H110 and 2400 and they do quite well.
Likewise the 210-grain Hornady JHP is a good bullet.
Go forth and shoot!