Shot a customized 58 yesterday in an IDPA shoot...used the 8.0 grains of Unique with a 210 Berry's plated bullet. No smoke and very quick to reload. Out of four stages I had one round out of the A-Zone... I'm not fast but I can hit what I aim at with that gun...
From a 4" barrel, I consider 1000-1200 fps as a Mid-Range load. The original Police loading was a 210 at 950+- from a 4". That is exactly what 8.0 grains of Unique will run a 210. Most of the full power 210s run in the mid to upper 1200s.
Lately I have been somewhat off-track with reloading .41s. I had a bunch of powder like 2400 and Blue Dot and a bunch of different weight cast bullets. So rather than waste Unique I loaded up a bunch of mid-range loads with bullets from 169-250 grains. Have yet to find an inaccurate load for a .41...
If you are looking for target velocity rounds, Reed's Ammo has .41 Special available.
Bob