Well there you go OP , two different sets of solutions for you !
Of course , in the first post you forgot to give desired velocity(s) . In this thread there has mostly been a presumption of * Regular Factory Load aka more or less BP equivalent * of 255gr @ 850-ish , maybe 825 from 4 inch . This is an excellent ballpark , and great choice for a single loading to do any and everything expected of a solid bullet , non magnum Big Bore , from paper punching to big game .
But we love to brag about how versatile .45 Colt is .
Drop down to " Cowboy Action " levels of +/- 700 fps for pleasant plinking . Your VV with cleaner and faster burning would work well here .
OR , if you believe as do Pearce and others that the 625 in .45Colt is capable of the same pressures as 625 in .45acp , you can bump up into the 900's .