Is it always the second shot from the magazine, i.e., the first one loaded by the semi-auto action? If so, it sounds like there is a feed issue and you are getting bullet setback as the round is being loaded. You might want to check that the magazine is ALL the way in. IIRC, the mags on some AR10 rifles fit pretty tight and need a good shove up the magwell. Also, are these FMJ or softpoints. If SP, there could be an edge that is catching the exposed lead as the action attempts to feed the round. This can also cause setback.