For full power loads I have been loading the Winchester 125 JHPs for decades with 21.7 grains of H110 lit off by a small pistol magnum primer. I have gone through over 8,000 of that projectile so far and have 3900 still sitting in the loading room waiting.
I LOVE the low throaty KAaaaBOOM that H110/296 yields

. I also get great accuracy from this load
I have burned well over 100 pounds of H110/296 over the last 40 years hand loading it in the 357 Magnum and the 41 Magnum cartridges
As to real world velocities for the 125 JHP, 357 loading (not test barrels) in a . . . . . .
2 1/8" Model 640 - 1234 FPS (AVG of 3 revolvers)
2 1/2" Model 19/66 - 1287 FPS (AVG of 2 revolvers)
3 1/2" Model 27 - 1315 FPS (AVG of 1 revolvers)
5" Model 627 - 1496 FPS (AVG of 2 revolvers)
6" Model 27 - 1531 FPS (AVG of 2 revolvers)
8" Python - 1599 FPS (AVG of 1 revolvers)
10" T/C Contender - 1780 FPS (AVG of 1 firearm)
18" Model 1982 - 2106 FPS (AVG of 1 lever gun)
These were strings of 5 shots per firearm all averaged together
For my target load I have been shooting a 150 grain SWC for many years now. Originally I drove it with Unique powder but I switched to W231 many years ago for how much cleaner it burns with the particular lube that is on my projectiles
I use 5.5 grains of powder lit up by a standard pistol primer. I have never really bothered to chronograph this because it shoots so well in most of my firearms I really didn't care how fast or slow it was going
While I have not really gotten too far into the project I am working on a load that uses a one 180 grain Remington semi-jacket hollow point.
The trick in this load will be that it needs to be subsonic even from my longest lever action rifle. I intend to use this with a suppressor on the lever gun so the target velovity 1000 FPS