Personally... I wouldn't take a Dremel to the cylinder stop/bolt, all of my guns didn't need a power tool and it's just too easy to overdo something quickly with a Dremel tool.
Also some revolvers like the Ruger SA New Model Blackhawk, due to the design of the lock work, it is just about impossible not to get a pronounced drag line.
There's two things you want to accomplish with the cylinder stop/bolt on a S&W, smooth up the surface on the top of the arch of the cyl stop that bears on the flat cylinder surface, and you want to "break" the sharp (angular) edges of the stop by putting a radius on it, so as the cylinder rotates against the edges, there's no sharp 90 degree edge to "scrape" against the cylinder surface
Both can be accomplished with just a few passes of wet/dry sandpaper under light pressure, followed by polishing with a paste like Flitz.
I usually use 800 grit sandpaper, if the surface is "rough" I use 600 grit to begin with and smooth with 800. Then I polish with Flitz on the end of a Q-tip.
This is my 432PD... I wish I was a better photographer.
In the "before" pic on the left, I was attempting to show how angular the edges are to the surface of the stop, but the flash washes it out. I also was trying to show how the surface of the cylinder stop at the apex of the arched surface, had a slight ridge across the surface that you could feel with your finger nail.
The two "after" pics shows how I was able to "knock down" the sharp edges of the stop, and smooth out the arched surface, with about a dozen or so light passes with some 800 grit wet/dry sandpaper. The flash reflection makes it look like I really rounded over the edges and removed metal, but I didn't. I just changed the shape of the edge from a 90 degree to a radius.
Then I polished it out to a mirror surface with a Q-tip dipped in Flitz polish... all in about 10 - 15 mins.